【基本信息】
姓名：牛庆芬
职称：副教授/硕士研究生导师
单位：半岛电竞app化学与制药工程学院，山东省分子工程重点实验室522
地址：济南市长清区大学路3501号
【研究方向】
1、有机合成化学及有机合成新方法
2、高效有机光伏材料的设计、合成及性能研究
3、新型高性能分子荧光探针的构建，包括可见光、近红外和双光子荧光探针的设计合成及应用研究
4、生物医学成像研究，包括活细胞、活组织及动物活体荧光成像研究
【教育工作背景】
2014年，半岛电竞app，副教授
2013年，山东大学，有机化学，博士
2008年，山东师范大学，化学，学士
【教研科研项目】
1. 校级研究生教育优质课程建设项目《合成化学》，2018，主持
2. 校级教研项目《化学化工“大类招生、分类培养”模式的实践与探索》，2015，主持
3. 山东省自然科学基金-- A-π-D-π-A型有机光伏给体材料的设计、合成及其性能研究，2017，主持
4. 山东省教改项目，2019，主持
【代表性学术论文】（发表SCI论文55余篇，被引频次1021次，H指数为22）
2019年
1. Zongrang Guo, Tingting Hu, Xingjian Wang, Tao Sun, Tianduo Li,* Qingfen Niu*, Highly sensitive and selective fluorescent sensor for visual detection of Cu2+ in water and food samples based on oligothiophene derivative, Journal of Photochemistry and Photobiology A: Chemistry 37 (2019) 50-58.
2. Yang Li, Qingfen Niu*, Tao Wei, Tianduo Li*, Novel thiophene-based colorimetric and fluorescent turn-on sensor for highly sensitive and selective simultaneous detection of Al3+ and Zn2+ in water and food samples and its application in bioimaging, Analytica Chimica Acta 1049 (2019) 196-212.
3. Zongrang Guo, Tingting Hu, Tao Sun, Tianduo Li*, Hong Chi, Qingfen Niu*, A colorimetric and fluorometric oligothiophene-indenedione-based sensor for rapid and highly sensitive detection of cyanide in real samples and bioimaging in living cells, Dyes and Pigments 163 (2019) 667–674.
4. Zongrang Guo, Qingfen Niu*, Tianduo Li, Tao Sun, Hong Chi, A fast, highly selective and sensitive colorimetric and fluorescent sensor for Cu2+ and its application in real water and food samples, Spectrochimica Acta Part A：Molecular and biomolecular spectroscopy 213 (2019) 97–103.
5. Zongrang Guo, Qingfen Niu*, Qingxin Yang, Tianduo Li, Hong Chi, A highly selective and sensitive dual-mode sensor for colorimetric and turn-on fluorescent detection of cyanidein water, agro-products and living cells, Analytica Chimica Acta1065 (2019) 113-123.
6. Junjie Wang, Tao Wei, Feng Ma, Tianduo Li*, Qingfen Niu*, A novel fluorescent and colorimetric dual-channel sensor for the fast, reversible and simultaneous detection of Fe3+ and Cu2+ based on terthiophene derivative with high sensitivity and selectivity, Journal of Photochemistry and Photobiology A: Chemistry 383 (2019) 111982.
7. Zhenyu Zuo*, Xiaomei Song, Dongyan Guo, Zongrang Guo, Qingfen Niu*, A dual responsive colorimetric/fluorescent turn-on sensor for highly selective, sensitive and fast detection of Fe3+ ions and its applications, Journal of Photochemistry and Photobiology A: Chemistry 382 (2019) 111876.
8. Zongrang Guo, Qingfen Niu*, Tianduo Li, Enhua Wang, Highly chemoselective colorimetric/fluorometric dual-channel sensor with fast response and good reversibility for the selective and sensitive detection of Cu2+, Tetrahedron 75 (2019) 3982–3992.
9. Junjie Wang, Qingfen Niu*, Tingting Hu, Tianduo Li, Tao Wei, A new phenothiazine-based sensor for highly selective, ultrafast, ratiometric fluorescence and colorimetric sensing of Hg2+: Applications to bioimaging in living cells and test strips, Journal of Photochemistry and Photobiology A: Chemistry 384 (2019) 112036.
10. Chunpeng Li, Qingfen Niu*, Shanshan Zhang, Tianduo Li, Qingxin Yang, Synthesis, photophysical and electrochemical properties of a new star-shaped molecule with a 1,3,5-triethynylbenzene core and diketopyrrolopyrrole arms, RSC Advances 9 (2019) 28357–28363.
11. Pengcheng Yin, Qingfen Niu*, Qingxin Yang, Linxin Lan, Tianduo Li, A new “naked-eye” colorimetric and ratiometric fluorescent sensor for imaging Hg2+ in living cells, Tetrahedron, 75 (2019) 130687.
12. Pengcheng Yin, Qingfen Niu,* Tao Wei, Tianduo Li,Yang Li, Qingxin Yang, A new thiophene-based dual functional chemosensor for ultrasensitive colorimetric detection of Cu2+ in aqueous solution and highly selective fluorimetric detection of Al3+ in living cells, Journal of Photochemistry and Photobiology A: Chemistry 2019, in press.
2018年
7. Linxin Lan, Qingfen Niu*, Tianduo Li, A highly selective colorimetric and ratiometric fluorescent probe for instantaneous sensing of Hg2+ in water, soil and seafood and its application on test strips, Analytica Chimica Acta 1023 (2018) 105-114.
8. Linxin Lan, Tianduo Li, Tao Wei, He Pang, Tao Sun, Enhua Wang, Haixia Liu, Qingfen Niu*, Oligothiophene-based colorimetric and ratiometric fluorescence dual-channel cyanide chemosensor: Sensing ability, TD-DFT calculations and its application as an efficient solid state sensor, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 193 (2018) 289–296.
9. Shanshan Zhang, Tao Sun, Dejun Xiao, Fang Yuan, Tianduo Li, Enhua Wang, Haixia Liu, Qingfen Niu*, A dual-responsive colorimetric and fluorescent chemosensor based on diketopyrrolopyrrole derivative for naked-eye detection of Fe3+ and its practical application, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 189 (2018) 594–600.
10. Tao Sun, Qingfen Niu*, Tianduo Li, Zongrang Guo, Haixia Liu, A simple, reversible, colorimetric and water-soluble fluorescent chemosensor for the naked-eye detection of Cu2+ in ~ 100% aqueous media and application to real samples, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 188 (2018) 411–417.
2017年
4. Shanshan Zhang, Qingfen Niu*, Tao Sun, Yang Li, Tianduo Li, Haixia Liu, The synthesis and properties of linear A–π–D–π–A type organic small molecule containing diketopyrrolopyrrole terminal units, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 183 (2017) 172–176.
5. Shanshan Zhang, Xingxing Wu, Qingfen Niu*, Zongrang Guo, Tianduo Li, Haixia Liu, Highly Selective and Sensitive Colorimetric and Fluorescent Chemosensor for Rapid Detection of Ag+, Cu2+ and Hg2+ Based on a Simple Schiff Base, Journal of Fluorescence 27 (2017) 729–737.
6. Tao Sun, Qingfen Niu*, Zongrang Guo, Tianduo Li, A simple highly sensitive and selective turn-on fluorescent chemosensor for the recognition of Pb2+, Tetrahedron Letters 58 (2017) 252-256.
7. Shanshan Zhang, Tao Sun, Zhen Xu, Tianduo Li, Yang Li, Qingfen Niu*, Haixia Liu, Novel biphenylene-diketopyrrolopyrrole-based A-π-D-π-A molecule: Synthesis, optical, electrochemical and electronical properties, Tetrahedron Letters 58 (2017) 2779-2783.
2. Qingfen Niu*, Xingxing Wu, Tianduo Li, Yuezhi Cui, Shanshan Zhang, Xiaoyan Li, Highly selective, sensitive and fast-responsive fluorescent sensor for Hg2+, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 163 (2016) 45–48.
3. Qingfen Niu*, Xingxing Wu, Tianduo Li, Yuezhi Cui, Shanshan Zhang, Qiuchen Su, A Phenylamine-Oligothiophene-Based Fluorescent Chemosensor for Selective Detection of Hg(II), Journal of Fluorescence 26 (2016) 1053–1058.
5. Xingxing Wu, Qingfen Niu*, Tianduo Li, Yuezhi Cui, Shanshan Zhang, A highly sensitive, selective and turn-off fluorescent sensor based on phenylamine-oligothiophene derivative for rapid detection of Hg2+, Journal of Luminescence 175 (2016) 182–186.
7. Qingfen Niu*, Xingxing Wu, Shanshan Zhang, Tianduo Li, Yuezhi Cui, Xiaoyan Li, A highly selective and sensitive fluorescent sensor for the rapid detection of Hg2+ based on phenylamine-oligothiophene derivative, Spectrochimica Acta Part A Molecular and biomolecular spectroscopy 153 (2016) 143-146.
8. Xingxing Wu, Shanshan Zhang, Qingfen Niu*, Tianduo Li*, A novel urea-derived fluorescent sensor for highly selective and sensitive detection of Fe3+, Tetrahedron Letters 57 (2016) 3407-3411.
9. Qiuchen Su, Qingfen Niu*, Tao Sun, Tianduo Li, A simple fluorescence turn-on chemosensor based on Schiff-base for Hg2+-selective detection, Tetrahedron Letters 57 (2016) 4297-4301.
1. Shanshan Zhang, Qingfen Niu*, Xingxing Wu, Tianduo Li, Yuezhi Cui, Xiaoyan Li, A Fast-Responsive Fluorescent Sensor for Hg2+ with High Selectivity and Sensitivity in Aqueous Media, Journal of Fluorescence 25 (2015) 1543–1548.
2. Qingfen Niu, Xiaohan Zhang, Shumiao Zhang, Xiaoyan Li, Hongjian Sun*, Activation of vinylic carbon-chlorine bond by nickel complexes supported with phosphine ligands, Inorganica Chimica Acta 426 (2015) 165-170.
2014-2012年
1. Qingfen Niu, Hongjian Sun, Lin Wang, Qingping Hu*, Xiaoyan Li*, Reactivity of mer-hydrido(2-mercaptobenzoyl)-tris(trimethylphosphine)cobalt( III ) complex, Dalton Trans. 43 (2014) 4059−4066.
2.Qingfen Niu, Hongjian Sun, Xiaoyan Li*, Synthesis, photophysical and thin-film self-assembly properties of novel fluorescent molecules with carbon–carbon triple bonds, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 133 (2014) 229–240.
3. Qingfen Niu, Yunqiang Lu, Hongjian Sun, Xiaoyan Li*, Xutang Tao*, Novel phenyl-oligothiophene derivatives containing acetylenic spacers for thin film materials: Synthesis, photophysical and morphology properties, Dyes and Pigments 97 (2013) 184−197.
4. Qingfen Niu, Hongjian Sun, Xiaoyan Li*, H.-F. Klein, Ulrich Flörke, Synthesis and Catalytic Application in Hydrosilylation of the Complex mer-Hydrido(2-mercaptobenzoyl)tris-(trimethylphosphine)cobalt(III), Organometallics 32 (2013) 5235−5238.
5. Qingfen Niu, Yunqiang Lu, Hongjian Sun, Xiaoyan Li*, Novel planar and star-shaped molecules: Synthesis, electrochemical and photophysical properties, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 107 (2013) 377–385.
6. Qingfen Niu, Xiaofeng Xu, Hongjian Sun, Xiaoyan Li*, Synthesis of 2-Mercaptobenzaldehyde, 2-Mercaptocyclohex-1-enecarboxaldehydes and 3-Mercaptoacrylaldehydes, Chin. J. Chem. 30 (2012) 2495–2500.
【学术兼职】
中国化学会会员；山东省化工协会会员；担任《Nanoscale》、《Current Organic Chemistry》、《Journal of Hazardous Materials》、《Sensors and Actuators B: Chemical》、《Analytical Chemistry》、《Analytica Chimica Acta》、《Analyst》、《Analytical Methods》、《Talanta》、《New Journal of Chemistry》、《Spectrochimica Acta Part A》、《Polymer Chemistry》、《RSC Advances》、《ACS Omega》、《ACS Sustainable Chemistry and Engineering》、《ACS Applied Materials & Interfaces》、《Dalton Transactions》、《Applied Organometallic Chemistry》、《Journal of Photochemistry and Photobiology A: Chemistry》、《Sensors》、《Food Chemistry》、《Inorganica Chimica Acta》、《Chemical Research in Toxicology》、《Small》、《Journal of the Chinese Chemical Society》等国际知名期刊的审稿专家。
【奖励与荣誉】
1. 山东省研究生优秀创新成果三等奖，共同指导教师，2019
2. 山东省优秀硕士学位论文2篇，共同指导教师，2019
3. 国家级研究生奖学金，共同指导教师，2019
4. 山东省省级教学成果二等奖，2018
5. 山东省研究生优秀科技创新成果三等奖，共同指导教师, 2018
6. 半岛电竞app研究生优秀硕士学位论文，共同指导教师，2018
7. 半岛电竞app研究生优秀创新成果二等奖，共同指导教师, 2018
8. 半岛电竞app研究生优秀创新成果一等奖，共同指导教师, 2017
9. 半岛电竞app研究生优秀创新成果三等奖，共同指导教师, 2017
10. 半岛电竞app大学生创新创业训练计划，指导教师, 2018
11. 国家级大学生创新创业训练计划，指导教师, 2019
12. 国家级大学生创新创业训练计划，指导教师, 2017
13. 国家级大学生创新创业训练计划，指导教师，2015
【教学经历】
1. 本科生课程：学术班《无机化学》、《无机化学实验》、《化学专业综合实验》及《毕业论文》
2. 硕士生课程：《现代有机合成化学》、《合成化学》
【研究生培养】
目前，培养研究生10名，已毕业研究生5名，其中1人考入中国科技大学攻读博士学位；1人进入山东中医药大学在编教师；1人从事高中教师职业；3人次获国家级研究生奖学金，多人获校级奖学金。
